Paper ID: 5

Amino Acid Substitution Equivalent to Human Chorea-acanthocytosis I2771R in Yeast Vps13 Protein Affects its Binding to Phosphatidylinositol 3-phosphate

Zoladek Teresa¹, Rzepnikowska Weronika², Flis Krzysztof², Kaminska Joanna², Grynberg Marcin¹, Urbanek Agnieszka³, Ayscough Kathryn³

¹ Institute of Biochemistry and Biophysics PAS (Poland)
² Institute of Biochemistry and Biophysics Polish Academy of Sciences (Poland)
³ University of Sheffield (United Kingdom)

Keywords:

Vps13, chorea-acanthocytosis, yeast model, actin cytoskeleton, binding of lipids, protein trafficking

Presented as:

  Poster [PS12-2] in PS12 Yeast as a model for human diseases and drug testing
  Oral presentation [W7-7] in W7 Proteostasis, ageing and disease models

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